Features of Way of Life in Women with Premenstrual Syndrome

  • L. V. Pakharenko Ivano-Frankivsk National Medical University
Keywords: premenstrual syndrome, risk factors


Today premenstrual syndrome (PMS) has leading positions in endocrine gynecology. In addition to hormonal, vegetative-vascular, metabolic mechanisms in the development of this disease biosocial factors are also important. The objective of research was to estimate features of lifestyle in women with PMS. The research included 200 women of reproductive age with diagnosis of PMS. Moos Menstrual Distress Questionnaire was used for diagnosis of this pathology. Control group consisted of 50 women without diagnosis of PMS. We found that lack of physical activity was associated with the presence of PMS (c2=20.90, p<0.001, OR=0.22, 95%CI=0.12-0.43, p<0.001). High percentage of individuals with irrational and unbalanced regime of work and rest was detected among women with this neuroendocrine syndrome (c2=4.39, p=0.04, OR=2.11, 95%CI=1.10-4.05, p=0.02). Specifically marked association of this factor was in patients with cephalgic form of the disease (c2=4.71, p=0.03, OR=3.73, 95%CI=1.23-11.29, p=0.02). Constant systematic stress situations in patients with PMS occurred much more frequently than in healthy women (c2=10.91, p<0,001, OR=3.88, 95% CI=1.73-6.89, p=0.001), and were the most typical for persons with neuropsychic form of the disease. Irregular diet was typical for patients of all PMS clinical forms (c2=12.75, p<0.001, OR=3.30, 95% CI=1.73-6.30, p<0.001). Thus, our results indicate the significance of certain biosocial factors in the incidence of this neuroendocrine syndrome. This will allow to predict PMS occurrence as well as to develop preventive measures of the disease taking into account risk factors.


Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Kaikhavandi Sattar. Epidemiology of Premenstrual Syndrome (PMS) – A Systematic Review and Meta-Analysis Study. J Clin Diagn Res. 2014 Feb; 8 (2): 106–9.

Matsumoto T, Asakura H, Hayashi T. Biopsychosocial aspects of premenstrual syndrome and premenstrual dysphoric disorder. Gynecol Endocrinol. 2013 Jan; 29 (1): 67-73.

Ministry of Public Health of Ukraine. Order #676 “Approval of clinical protocols for obstetric and gynecological care”. 2004.

Nagata C, Hirokawa K, Shimizu N, Shimizu H. Soy, fat and other dietary factors in relation to premenstrual symptoms in Japanese women. BJOG. 2004 Jun; 111 (6): 594-9.

Smetnik VP, Tymilovich LG, editors. Neoperative Gynecology: Guidance for doctors. Book 1. – SPb.: SOTIS; 1995. p. 129-38.

Teixeira AL, Oliveira ÉC, Dias MR. Relationship between the level of physical activity and premenstrual syndrome incidence. Rev Bras Ginecol Obstet. 2013 May; 35 (5): 210-4.

Original Research