Abstract
The objective is to investigate the influence of stress on the clinical and pathogenetic peculiarities of the course of stable coronary heart disease (SIHD) in conjunction with atrial fibrillation (AF).
Materials and methods. The analysis of psychodiagnostic tests, labolatory and instrumental research methods in patients with and without AF has been performed. Patients were divided into three groups: group 1 – patients with stable ischemic heart disease (SIHD) with a constant form of AF (15 patients were examined), group 2 – patients with SIHD with paroxysmal form of AF (16 patients were examined), group 3 – patients with SIHD without AF (15 patients were examined).
Results. According to the analysis of the data obtained, low level of stress was found in 6 (37.50%) patients with a permanent form of AF, whereas in patients without AF, it was observed in 1 (6.67%) person (p1<0.05) (p1 – the reliability of the differences in indicators relative to patients without AF). Moderate somatic disorder in women with paroxysmal AF was significantly higher than in the group of patients with a constant form of AF (p2<0.05) (p2 – the reliability of the differences in the indicators relative to patients with a constant form of AF). It is confirmed in patients with AF there are signs of the average stress level on the perceived stress level-10 (p2<0.05). Among the social factors that may have an impact on health are the influence of the media, the use of alcohol by relatives, the threat of unemployment for relatives and friends. These indicators were most often found in the group of patients with AF rather than without it (p2<0.05). Changes of ECG and echocardiographic parameters in all groups of patients were revealed.
Conclusion. The association of stress with stable ischemic heart disease combined with atrial fibrillation has shown that stress disorders are associated with an increased risk of atrial fibrillation and may worsen their course and predict the risk of developing paroxysm. The dependence between the severity of clinical manifestations, psychodiagnostic tests, laboratory methods, ECG and echocardiographic parameters of the heart on the course of atrial fibrillation is proved.
References
Svensson T, Kitlinski M, Engström G. Psychological stress and risk of incident atrial fibrillation in men and women with known atrial fibrillation genetic risk scores. Sci Rep. 2017; 7: 42613. DOI: https://doi.org/10.1038/srep42613 [PMid:28195211 PMCid:PMC5307347]
KniazkovaII. Psychosocial factors and arterial hypertension. Zdorovya Ukrayiny. 2016;10(383):37-39.
Garg PK, O'Neal WT, Diez-Roux AV. Negative affect and risk of atrial fibrillation: MESA. Am Heart Assoc. 2019; 8(1): e010603. DOI: https://doi.org/10.1161/JAHA.118.010603 [PMid:30563392 PMCid:PMC6405728]
Belialov FI. Depression, anxiety and stress in patients with coronary heart disease. Terapevticheskii arhiv. 2017;8:104-109. DOI: https://doi.org/10.17116/terarkh2017898104-109 [PMid:28914859]
Patel D, Mc Conkey ND, Sohaney R. A Systematic Review of Depression and Anxiety in Patients with Atrial Fibrillation: The Mind-Heart Link. Cardiovasc Psychiatry Neurol. 2013; 2013:159850. DOI: https://doi.org/10.1155/2013/159850 [PMid:23710335 PMCid:PMC3655604]
Shi S, Liu T, Liang J. Depression and Risk of Sudden Cardiac Death and Arrhythmias: A Meta-Analysis. Psychosom Med. 2017;79(2):153-161.
Katerenchuk IP. Atrial fibrillation: modern aspects of diagnosis and treatment. Practykuiuchуi likar. 2012;4:61-71.
Kypnovytska IH. Prevention of amiodarone-induced thyroid dysfunction in patients with atrial fibrillation by correction of oxidative stress and endogenous intoxication. Ukrainskyi terapevtychny zhurnal. 2013; 1:18.
Kornatskyy VM. Influence of psychoemotional disorders on the development and course of cardiovascular pathology. Ukrayinskyi kardiologichny zhurnal. 2008;6:94-100.
Kornatskyy VM. Methodology of prevention and early diagnostics of circulatory system diseases in modern conditions. Ukrainskyi kardiologichny zhurnal. 2015;1:75-79.
Baranova EI. Atrial fibrillation in patients with arterial hypertension. Arterialnaya gipertenziya. 2011;4:293-304. DOI: https://doi.org/10.18705/1607-419X-2011-17-4-293-304
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