65 patients with arterial hypertension (AH) along with a co-occurring chronic obstructive pulmonary disease (COPD) were examined. They were divided into two treatment groups: the first group received only drug therapy (DT) that included verapamil and sydnofarm (DT-1), the second group received additional laser therapy (DT - 2). Arterial hypertension in patients with COPD was characterized by increased hypertension load mainly at night with exaggerated type and inadequate nocturnal BP decrease (“non-dipper” and “night-picker”). Both speed and volume parameters of the function of external respiration were changed in case of combining COPD and AH. According to echocardiographic parameters patients with COPD along with a co-occurring AH developed concentric hypertrophy, infraction of diastolic function while maintaining systolic against a background of high heart rate, and increased variability of blood pressure. It was the maladaptive cardiac remodeling. We concluded that it is advisable to use antihypertensive drugs of the group of slow calcium channel antagonists (verapamil) and venous vasodilators (sydnofarm) in patients with COPD along with a co-occurring AH. Complex treatment in combination with the low intensity laser radiation (LILR) led to improvement of the most parameters of the function of external respiration that was combined with the positive changes in subjective data, BP profile echocardiographic parameters. The complex of drug and non-drug types of therapy for patients with hypertension along with a co-occurring COPD which includes verapamil, sydnofarm and the LILR is adequate in terms of improving the quality of patient’s life.
Feshchenko Yu.I., Dziublyk Ya.O., Havrisiuk V.K., Mostovyi Yu.M. Chronic obstructive pulmonary disease: etiology, pathogenesis, classification, diagnosis and therapy: guideline. Kyiv. 2013; 52.
Bohatyriovа R.V., Kovalenko V.M. National strategy for the prevention and treatment of arterial hypertension in Ukraine. К. МОRІОN. 2012; 120.
Shelygin S.I., Кlodchenko N.N., Zarembo I.А. The use of laser therapy in the clinic of internal diseases: guideline. Luhansk. 1990; 17.
Schultz R.Yu., Orekhova E.M., Kotenko K.V. Effect of different regimens of laser therapy on blood pressure in hypertensive patients. Nauchno-prakt. zhurnal “Fizioterapiya, balneologiya i reabilitatsiya”. 2006; 6: 58-60.
Goncharova I.A. Application of laser and chromotherapy in treatment of hypertension with concomitant somatic pathology: thesis. Voronezh. 2012; 22.
Dzyak G.V. Efficacy of ivabradine in patients with cardiorespiratory disorders. Ukraiinskyi pulmonilohichnyi zhurnal. 2008; 3: 55.
Misiuna A.V., Matsehora N.A. A method of treating patients with hypertension along with a co-occurring chronic obstructive pulmonary disease. Patent for utility model №89236 Ukraine .2014; 7: 6.
Starodubova A.V., Kopelev A.A. Ambulatory blood pressure monitoring. Lechebnoye delo. 2010; 1: 59-67.
Radchenko H.D., Hranіch V.M. Assessment of echocardiographic and electrocardiographic evidence of left ventricular hypertrophy in patients with arterial hypertension before and after treatment in a specialized department (5-year follow-up). Novosti meditsiny i farmatsii. 2007; 216: 12-13.
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