Features of Restructuring of the Excretory Ducts of the Submandibular Gland in Case of Experimental Diabetes Using the Principal Component Analysis


submandibular gland
streptozotocin-induced diabetes
principal component analysis

How to Cite

Kotyk, T. L. (2015). Features of Restructuring of the Excretory Ducts of the Submandibular Gland in Case of Experimental Diabetes Using the Principal Component Analysis. Galician Medical Journal, 22(3), 16-22. Retrieved from https://ifnmujournal.com/gmj/article/view/331


Features of restructuring of the intercalated, granular and striated ducts of the submandibular gland in rats in case of streptozotocin-induced diabetes were determined using the principal component analysis. The results revealed that restructuring and priority of the changes of ducts depend on the duration of the experiment. Dysfunction of the ducts was observed beginning from the twenty-eighth day of the experiment which was confirmed by the restructuring of principal components. The functional capacity of epithelial cells of granular and striated ducts was found to be the most sensitive to pathogenic factors accompanying diabetes. The sequence and extent of pathological changes having the greatest effect on the development of dysfunction of the ducts were also identified.




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