Macro- and Microscopic Structural Features of the Cerebellar Dentate Nucleus in Humans
PDF

Keywords

nuclei
cerebellum
macro-microscopy

How to Cite

Shyian, D. M. (2015). Macro- and Microscopic Structural Features of the Cerebellar Dentate Nucleus in Humans. Galician Medical Journal, 22(3), 40-43. Retrieved from https://ifnmujournal.com/gmj/article/view/337

Abstract

Since ancient times the study of one part of the brain - the cerebellum - has attracted the attention of many researchers, however, neither anatomy of the cerebellum, nor its function remain fully studied. The nuclei of the cerebellum, including the dentate nucleus are not sufficiently studied. The structural features of the cerebellar dentate nucleus of human in ontogenesis and its topographic and anatomic location are important not only for anatomists, physiologists, but also for clinicians in order to solve any questions relating to the pathology of the nervous system successfully.The study of the structure of the cerebellar dentate nucleus and its functional features is necessary for clinicians to elaborate rational operational accesses to its formations, and establish the exact boundaries of localization of pathological processes in the dentate nucleus of the cerebellum and adjoining white matter. In this context, the objective of this study was to establish macro- and microscopic features of the dentate nucleus of the cerebellum. The study was carried out on 340 preparations of human cerebellum using traditional and modern morphological methods: macroscopic, macro- and microscopic, morphometric, histotopographical, histological (hematoxylin and eosin staining, resorcin-fuchsin staining (Krutsay), Pat. 65245 Ukraine, the Method of Histological Staining of Nerve Fibers) and statistical analysis. Macro- and microscopic features of the dentate nucleus were established. On the series of cerebellar sections in a horizontal, frontal and sagittal planes, as well as macro-microscopic preparations of cerebellar dentate nucleus, topographo-anatomical location, shape, line size, structure and course of grey plate were established. The peculiarities of macro- and microscopic histological structure of the dentate nucleus of the cerebellum were described. Own classification of convolutions and teeth of dentate nucleus of the cerebellum was established.

PDF

References

Gavasheli O.A. Anatomical features of the cerebellar dentate nucleus. Voprosy morfologiyi nervnoy sistemy. Moscow. Medgiz. 1960; 33-39.

Kasym-Khodzhayev I.K., Dzhumabayev E.S., Kosymkhozhyyev M.I. Structural changes in the nuclei of the extrapyramidal system, Purkinje cells and dentate nucleus of the cerebellum after the amputation of the right rear limb in dogs. Morfologiya. 2008; 133(4): 73.

Vasin N.Ya., Lesov N.S., Mayorchik V.E. Clinical and physiological effects of electrical stimulation and destruction of the ventrolateral divisions of the dentate nuclei of the cerebellum in various forms of musculoskeletal pathology. Voprosy neyrokhirurgiyi. 1977; 4: 14-17.

Shyian D.M., Korobkova L.K., Lupyr V.M. Pat. 55427 Ukraine, IPC G01N 1/30. Method of staining brain specimens. Kharkiv National Medical University. - No u201007778; appl. 06. 21. 2010, publ. 12.10.2010, bull. No 23.

Goncharov N.I., Speranskiy L.S., Krayushkin A.I., Dmitriyenko S.V. Guidance on the preparation and manufacture of anatomical specimens. N. Novgorod. NGMA. 2002; 192.

Khachatryan V.A., Asatryan E.A., Mamatkhanov M.R. Stimulation of the cerebellum in the surgical treatment of pharmacoresistant epilepsy (review of literature). Neyrokhirurgiya i nevrologiya detskogo vozrasta. 2014; 2(40): 53-67.

Kheyns D. Neuroanatomy: Neuroanatomy: atlas of structures, sections and systems. Moscow. Logosfera. 2008; 344.

Shyian D.M. Method of the investigation of morphological features of the structure of the dentate nucleus. Morfofunktsionalnye osobennosti nervnoi, sosudistoy i endokrinnoy system v norme i pod vliyaniyem nekotorykh faktorov: materialy nauchno-prakticheskoi konferentsiyi s mezhdunarodnim uchastiyem, posvashchennoy 165-letiyu so dnya rozhdeniya vydayushchegosya anatoma A.K. Belousova, 11.15. 2013. Ministry Of health Care of Ukraine. Kharkiv National Medical University. Kharkiv. 2013; 88.

Shyian D.M. Morphometric features of the dentate nucleus. Halytskyi likarskyi visnyk. 2013; 20(1,2): 94-95.

Sawa N., Kataoka H., Kiriyama T. et al. Cerebellar dentate nucleus in progressive supranuclear palsy. Clin Neurol Neurosurg. 2014; 118: 32−36.

Diedrichsen J., Maderwald S., Küper M. et al. Imaging the deep cerebellar nuclei: a probabilistic atlas and normalization procedure. Neuroimage. 2011; 1(3): 1786−1794.

Akakin A., Peris-Celda M., Kilic T. et al. The dentate nucleus and its projection system in the human cerebellum: the dentate nucleus microsurgical anatomical study. Neurosurgery. 2014; 74(4): 401−424.

Stefanescu M.R., Thürling M., Maderwald S. et al. 7T fMRI study of cerebellar activation in sequential finger movement tasks. Exp. Brain Res. 2013; 228(2): 243−254.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.