The objective of the research was to study and investigate the efficiency of Thiotriazolin combined with antihypertensive drugs in connection with background therapy (BT) on the daily dynamics of blood pressure (BP) in comparison with the use of antihypertensive drugs only in connection with BT.
Results of the research: Positive dynamics in the reduction of the frequency of the disease subjective clinical signs manifestations in two research groups was observed (р<0.05). Significant decrease in pain syndrome and dyspnea was detected in patients with myocardial infarction (MI) and concomitant arterial hypertension (AH). The use of BT with ramipril and thiotriazolin ensured a gradual increase in the number of patients with the most favorable profile “diрper”. The inclusion of ramipril to BT or its combination with thiotriazolin resulted in a significant decrease in diastolic blood pressure (DBP) variability. Dynamics of systolic blood pressure (SBP) morning rise rate was analyzed. Morning rise rate (MRR) of systolic blood pressure significantly decreased in 3 months of investigation in patients treated with BT and ramipril or its combination with thiotriazolin.
Conclusions: due to combined treatment with ramipril and thiotriazolin in connection with BT a greater number of patients achieved BP target level and decreased BP morning rise indicators.
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