Assessment of Clinical Course Intensity of Premenstrual Syndrome


premenstrual syndrome

How to Cite

Pakharenko, L. V. (2015). Assessment of Clinical Course Intensity of Premenstrual Syndrome. Galician Medical Journal, 22(4), 92-95. Retrieved from


Premenstrual Syndrome (PMS) is one of the most common neuroendocrine disorders in gynecology. Diagnosis of this disease, which can completely cover the total clinical picture remains to be discussed.

The objective of the research was to study the intensity of clinical manifestations in women with PMS.

Material and methods. The research included 200 women of reproductive age with diagnosis of PMS. Moos Menstrual Distress Questionnaire was used for diagnosis of this pathology. Control group consisted of 50 women without diagnosis of PMS.

Results of the study. We found differences in the spread and severity of symptoms of diseases between women with different clinical forms. The item “sensation of pain ” was found to be the highest in patients with cephalgic and crisis forms and exceeded the indicator of healthy individuals, respectively, in 4.05 (p<0.001) and 4.09 times (p<0.001). The item “impaired concentration” was in 2.94 times (p<0.001) higher in women with neuropsychical form compared with that of healthy women. The most severe “behavioral change” was determined in patients with cephalgic and crisis forms of PMS whose indices were in 3.31 times (p<0.001) higher about the control. Item “ vegetative reaction” in women with crisis and cephalgic forms was higher than in healthy women, respectively, in 4.27 (p<0.001) and 3.42 times (p<0.001). The most intense “fluid retention” was observed in patients with edematous form. The index of item “negative affect” was particularly severe in women with neuropsychical form, “activity disorder” in patients with crisis and cephalgic forms of PMS. Item “control” was typical only for women with crisis form, which increased in 4.84 times (p<0.001) compared with healthy ones.

Conclusions. Moos Menstrual Distress Questionnaire is the diagnostic method that allows to estimate not only the presence but also the intensity of the specific symptoms of PMS.



Order of the Ministry of Health of Ukraine “On approval of clinical protocols for obstetric and gynecological care” (December 31, 2004).

Smetnik VP, Tumilovich LG. Non-operative gynecology: Guide for Physicians. Book 1. Saint-Petersburg. 1995; 129-138.

Bentz D, Steiner M, Meinlschmidt G. SIPS – screening instrument for premenstrual symptoms. The German version of Premenstrual Symptoms Screening Tool to assess clinically relevant disturbances. Nervenarzt. 2012; 83 (1): 33-39.

Wu L, He Z, Zhao H. [et. al] Chinese version of Daily Record of Severity of Problems: reliability and validity. J. Adv.Nurs. 2013; 69 (2): 449-456.

International statistical classification of diseases and related health problems. 10th Revision, 2nd ed. / World Health Organization. Geneva, 2007.

Nyberg S. How to determine symptom severity in premenstrual syndrome: a combination of daily symptom ratings and interviews. Sex. Reprod. Healthc. 2011; 2 (4): 161-168.

Ross C, ColemanG, Stojanovska C. Factor structure of the modified Moos Menstrual Distress Questionnaire: assessment of prospectively reported follicular, menstrual and premenstrual symptomatology. J. Psychosom. Obstet. Gynaecol. 2003; 24 (3): 163-174.

Hariri FZ, Moghaddam-Banaem L, Siah Bazi S [et al.]The Iranian version of the Premenstrual Symptoms Screening Tool (PSST): a validation study. Arch. Womens Ment. Health. 2013; 16 (6): 531-537.

O'Brien P M, RapkinA, Schmidt P [et al] The Premenstrual Syndromes: PMS and PMDD. Informa Healthcare. 2007; 198.

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