Immediate implant placement and loading can be done in a compromised bone. Curettage, cleaning of the whole area up to good bone quality and primary stability are the main necessities for success. The effect of local application of scaffold-like preparation rich in growth factors (PRGF) on bone regeneration in artificial defects and the potential effect of humidifying titanium dental implants with liquid PRGF on their osseointegration were investigated. The PRGF formulations were obtained from venous blood of three goats and applied either as a 3D fibrin scaffold (scaffold-like PRGF) in the regeneration of artificial defects or as liquid PRGF via humidifying the implants before their insertion. PRGF can accelerate bone regeneration in artificial defects and improve the osseointegration of titanium dental implants. The stability and healing around implants immediately placed into extraction sockets and augmented with different bone graft materials were evaluated. Comparative analysis of implants subjected to immediate functional loading and immediate nonfunctional loading compared to a conventional loading protocol was made.
Piuryk VP, Ozhohan ZG, Makhlynets NP, Piuryk YV. A method of treating postoperative wounds of the oral mucosa. Ukraine’s patent UA 51699. 2010 July 26.
Rozhko MM, Mykhailenko TM, Paliichuk IV, et al. Dentistry. Nova Zoria. Ivano-Frankivsk. 2007;1:156-178.
Branemark P-I. Osseointegration and its experimental background. The Journal of Prosthetic Dentistry.2015;50(3):399-410.
Koh RU, Rudek I, Wang H-L. Immediate implant placement: positives and negatives. Implant Dentistry. 2010;19(2):98-108. doi: 10.1097/ID.0b013e3181d47eaf.
Jofre J, Valenzuela D, Quintana P, Asenjo-Lobos C. Protocol for immediate implant replacement of infected teeth. Implant Dentistry. 2012;21(4):287-294. doi: 10.1097/ID.0b013e31825cbcf8.
Chen ST, Wilson Jr TG, Hammerle CHF. Immediate or early placement of implants following tooth extraction: review of biologic basis, clinical procedures, and outcomes. The International Journal of Oral & Maxillofacial Implants. 2004;19 Suppl:12-25.
Esposito M, Grusovin MG, Polyzos IP, Felice P, Worthington HV. Timing of implant placement after tooth extraction: immediate, immediate-delayed or delayed implants? A Cochrane systematic review. European Journal of Oral Implantology. 2010;3(3):189-205.
Fugazzotto PA. Treatment options following single-rooted tooth removal: a literature review and proposed hierarchy of treatment selection. Journal of Periodontology. 2005;76(5):821-831.
Schropp L, Isidor F. Timing of implant placement relative to tooth extraction. Journal of Oral Rehabilitation. 2008; 35 Suppl 1:33-43. doi: 10.1111/j.1365-2842.2007.01827.x.
Rieder D, Eggert J, Krafft T, Weber H-P, Wichmann MG, Heckmann SM. Impact of placement and restoration timing on single-implant esthetic outcome - a randomized clinical trial. Clinical Oral Implants Research. 2014; doi: 10.1111/clr.12539.
Anthony Feck. Predictable, atraumatic dental extractions. Dental Economics. Available from: http://www.dentaleconomics.com/articles/print/volume-100/issue-10/features/predictable-atraumatic-dental-extractions.html
Peterson L, Ellis E, Hupp J, Tucker M, Contemporary Oral and Maxillofacial Surgery, 3rd ed. St. Louis Mosby. 1998;797.
Little J, Dental Management of the Medically Compromised Patient. 6th ed. 2002;736.
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