Primary aggressive chondroblastoma of the tibia
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Keywords

chondroblastoma
benign
aggressive
primary
metastases

How to Cite

Badaoui, R., Elmaqrout, A., Boussaidan, M., Mekaoui, J., Boukhriss, J., Chafry, B., Benchaba, D., & Boussouga, M. (2020). Primary aggressive chondroblastoma of the tibia: a case report and review of the literature. Galician Medical Journal, 27(2), E202021. https://doi.org/10.21802/gmj.2020.2.1

Abstract

Chondroblastoma is a primary bone tumor in children, adolescents and young adults, which accounts for 1% of all bone tumors. Epiphyseal or epiphysometaphyseal localization, this lesion usually develops from secondary ossification centers close to the knee, shoulder and hip. Although chondroblastoma is a nonaggressive benign tumor, it can very rarely show a locally aggressive character or a malignant transformation or even metastases. We describe a histologically proven case of an aggressive, primary chondroblastoma of the tibia invading soft tissue in a 22-year-old girl.

https://doi.org/10.21802/gmj.2020.2.1
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References

Chen W, DiFrancesco LM. Chondroblastoma: An Update. Arch. Pathol. Lab. Med. 2017 Jun;141(6):867-871. DOI: https://doi.org/10.5858/arpa.2016-0281-RS [PMid:28557595]

Jaffe HL, Lichtenstein L. Benign chondroblastoma of bone: reinterpretation ofthe so-called calcified or chondromatous giant cell tumors. Am J Pathol 1942;18:969-991.

Dahlin DC, Ivins JC. Benign chondroblastoma. A review of 125 cases. Cancer 1972;30:401-1. DOI: https://doi.org/10.1002/1097-0142(197208)30:2<401::AID-CNCR2820300216>3.0.CO;2-B

Cannon CP, Nelson SD, Seeger LL, Eckardt JJ. Clear cell chondrosarcoma mimicking chondroblastoma in a skeletally immature patient.Skeletal Radiol 2002;31:369-372 DOI: https://doi.org/10.1007/s00256-002-0519-7 [PMid:12073124]

Soder S, Oliveira AM, Inwards CY, Muller S, Aigner T. Type II collagen, but not aggrecan expression, distinguishes clear cell chondrosarcoma and chondroblastoma. Pathology 2006;38:35-38. DOI: https://doi.org/10.1080/00313020500455803 [PMid:16484006]

Schajowicz F, Gallardo H. Epiphysial chondroblastoma of bone. A clinico-pathological study of sixty-nine cases. J Bone Joint Surg [Br] 1970;52:205-226. DOI: https://doi.org/10.1302/0301-620X.52B2.205

Springfield DS, Capanna R, Gherlinzoni F, Picci P, Campanacci M. Chondroblastoma. A review of seventy cases. J Bone Joint Surg [Am] 1985;67:748-755. DOI: https://doi.org/10.2106/00004623-198567050-00009

Ramappa AJ, Lee FY, Tang P, Carlson JR, Gebhardt MC, Mankin HJ. Chondroblastoma of bone. J Bone Joint Surg [Am] 2000;82:1140-1145. DOI: https://doi.org/10.2106/00004623-200008000-00011

Huvos AG, Higinbotham NL, Marcove RC, O'Leary P. Aggressive chondroblastoma. Review of the literature on aggressive behavior and metastases, with a report of one new case. Clin Orthop 1977;126:266-272. DOI: https://doi.org/10.1097/00003086-197707000-00051

Jambhekar NA, Desai PB, Chitale DA, Patil P, Arya S. Benign metastasizing chondroblastoma. A case report. Cancer 1998;82:675-678.100 DOI: https://doi.org/10.1002/(SICI)1097-0142(19980215)82:4<675::AID-CNCR9>3.0.CO;2-K

Corsat JP, Tomeno B, Forest M, Vinh TH. Chondroblastomes bénins : une revue de 30 cas. Rev Chir Orthop 1989;75:179-187.

Hull MT, Gonzales-Crussi F, DeRosa GP, Graul RS.Aggressive chondroblastoma: Report of a case with multiple bone and soft tissue involvement. Clin Orthop Related Res 1977;126:2615. DOI: https://doi.org/10.1097/00003086-197707000-00050

Quint LE, Gross BH, Glazer GM, Braunstein EM, White SJ. J Comput Assist Tomog 1984;8:907-910. DOI: https://doi.org/10.1097/00004728-198410000-00020 [PMid:6470260]

Kim J, Kumar R, Raymond AK, Ayala AG. Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature. Skeletal Radiol 2010;39(6):583-587. DOI: https://doi.org/10.1007/s00256-009-0833-4 [PMid:19936740]

Vialle R, Feydy A, Rillardon L, Tohme-Noun C, Anract P, Colombat M, et al. Chondroblastoma of the lumbar spine. Report of two cases and review of the literature. J Neurosurg Spine 2005;2(5):596-600. DOI: https://doi.org/10.3171/spi.2005.2.5.0596 [PMid:15945435]

Wright JL, Sherman MS. An unusual chondroblastoma. J Bone Joint Surg Am 1964;46:567-600. DOI: https://doi.org/10.2106/00004623-196446030-00017

Erler K, Yildiz C, Demiralp B, Ozdemir MT, Basbozkurt M. Chondroblastoma of the distal femur. A case report. Acta Orthop Belg 2003;69(5):467-472

Harish K, Janaki MG, Alva NK. "Primary" aggressive chondroblastoma of the humerus: a case report. http://www.biomedcentral.com/1471-2474/5/9; 2004. DOI: https://doi.org/10.1186/1471-2474-5-9 [PMid:15113430 PMCid:PMC395834]

McLaughlin RE, Sweet DE, Webster T, Merritt WM: Chondroblastoma of the pelvis suggestive of malignancy. Report of an unusual case treated by wide pelvic excision. J Bone Joint Surg Am 1975, 57:549-551. DOI: https://doi.org/10.2106/00004623-197557040-00021

Varma BP, Gupta IM: Atypical chondroblastoma of tibia. Report of a recurrent lesion. Clin Orthop 1972, 89:241-245. DOI: https://doi.org/10.1097/00003086-197211000-00031

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